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Chtop (Chromatin target of Prmt1) auto-regulates its expression level via intron retention and nonsense-mediated decay of its own mRNA

Chtop (chromatin target of Prmt1) regulates various aspects of gene expression including transcription and mRNA export. Despite these important functions, the regulatory mechanism underlying Chtop expression remains undetermined. Using Chtop-expressing human cell lines, we demonstrate that Chtop exp...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Izumikawa, Keiichi, Yoshikawa, Harunori, Ishikawa, Hideaki, Nobe, Yuko, Yamauchi, Yoshio, Philipsen, Sjaak, Simpson, Richard J, Isobe, Toshiaki, Takahashi, Nobuhiro
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175361/
https://ncbi.nlm.nih.gov/pubmed/27683223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw831
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