Chtop (Chromatin target of Prmt1) auto-regulates its expression level via intron retention and nonsense-mediated decay of its own mRNA

Chtop (chromatin target of Prmt1) regulates various aspects of gene expression including transcription and mRNA export. Despite these important functions, the regulatory mechanism underlying Chtop expression remains undetermined. Using Chtop-expressing human cell lines, we demonstrate that Chtop exp...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Izumikawa, Keiichi, Yoshikawa, Harunori, Ishikawa, Hideaki, Nobe, Yuko, Yamauchi, Yoshio, Philipsen, Sjaak, Simpson, Richard J, Isobe, Toshiaki, Takahashi, Nobuhiro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2016
Konular:
Molecular Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175361/
https://ncbi.nlm.nih.gov/pubmed/27683223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw831
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