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Visceral hypersensitivity in inflammatory bowel diseases and irritable bowel syndrome: The role of proteases

Proteases, enzymes catalyzing the hydrolysis of peptide bonds, are present at high concentrations in the gastrointestinal tract. Besides their well-known role in the digestive process, they also function as signaling molecules through the activation of protease-activated receptors (PARs). Based on t...

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Veröffentlicht in:World J Gastroenterol
Hauptverfasser: Ceuleers, Hannah, Van Spaendonk, Hanne, Hanning, Nikita, Heirbaut, Jelena, Lambeir, Anne-Marie, Joossens, Jurgen, Augustyns, Koen, De Man, Joris G, De Meester, Ingrid, De Winter, Benedicte Y
Format: Artigo
Sprache:Inglês
Veröffentlicht: Baishideng Publishing Group Inc 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175241/
https://ncbi.nlm.nih.gov/pubmed/28058009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v22.i47.10275
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