BACH1 Promotes Temozolomide Resistance in Glioblastoma through Antagonizing the Function of p53

The acquisition of drug resistance is a persistent clinical problem limiting the successful treatment of glioblastoma (GBM). However, the molecular mechanisms by which initially chemoresponsive tumors develop therapeutic resistance remain poorly understood. In this study, we report that BACH1, a hem...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Nie, Er, Jin, Xin, Wu, Weining, Yu, Tianfu, Zhou, Xu, Zhi, Tongle, Shi, Zhumei, Zhang, Junxia, Liu, Ning, You, Yongping
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175153/
https://ncbi.nlm.nih.gov/pubmed/28000777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39743
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