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BACH1 Promotes Temozolomide Resistance in Glioblastoma through Antagonizing the Function of p53
The acquisition of drug resistance is a persistent clinical problem limiting the successful treatment of glioblastoma (GBM). However, the molecular mechanisms by which initially chemoresponsive tumors develop therapeutic resistance remain poorly understood. In this study, we report that BACH1, a hem...
Enregistré dans:
Publié dans: | Sci Rep |
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Auteurs principaux: | , , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Nature Publishing Group
2016
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5175153/ https://ncbi.nlm.nih.gov/pubmed/28000777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39743 |
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