BACH1 Promotes Temozolomide Resistance in Glioblastoma through Antagonizing the Function of p53

The acquisition of drug resistance is a persistent clinical problem limiting the successful treatment of glioblastoma (GBM). However, the molecular mechanisms by which initially chemoresponsive tumors develop therapeutic resistance remain poorly understood. In this study, we report that BACH1, a hem...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Nie, Er, Jin, Xin, Wu, Weining, Yu, Tianfu, Zhou, Xu, Zhi, Tongle, Shi, Zhumei, Zhang, Junxia, Liu, Ning, You, Yongping
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175153/
https://ncbi.nlm.nih.gov/pubmed/28000777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39743
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