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Reprogramming of a melanoma genome by nuclear transplantation

We have used nuclear transplantation to test whether the reprogramming activity of oocytes can reestablish developmental pluripotency of malignant cancer cells. We show here that the nuclei of leukemia, lymphoma, and breast cancer cells could support normal preimplantation development to the blastoc...

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Publicat a:Genes Dev
Autors principals: Hochedlinger, Konrad, Blelloch, Robert, Brennan, Cameron, Yamada, Yasuhiro, Kim, Minjung, Chin, Lynda, Jaenisch, Rudolf
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC517407/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15289459/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1213504
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