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Reprogramming of a melanoma genome by nuclear transplantation

We have used nuclear transplantation to test whether the reprogramming activity of oocytes can reestablish developmental pluripotency of malignant cancer cells. We show here that the nuclei of leukemia, lymphoma, and breast cancer cells could support normal preimplantation development to the blastoc...

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Detalhes bibliográficos
Main Authors: Hochedlinger, Konrad, Blelloch, Robert, Brennan, Cameron, Yamada, Yasuhiro, Kim, Minjung, Chin, Lynda, Jaenisch, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC517407/
https://ncbi.nlm.nih.gov/pubmed/15289459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1213504
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