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Reprogramming of a melanoma genome by nuclear transplantation

We have used nuclear transplantation to test whether the reprogramming activity of oocytes can reestablish developmental pluripotency of malignant cancer cells. We show here that the nuclei of leukemia, lymphoma, and breast cancer cells could support normal preimplantation development to the blastoc...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Principais autores: Hochedlinger, Konrad, Blelloch, Robert, Brennan, Cameron, Yamada, Yasuhiro, Kim, Minjung, Chin, Lynda, Jaenisch, Rudolf
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2004
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC517407/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15289459/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1213504
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