Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei

To assess the extent of abnormal gene expression in clones, we assessed global gene expression by microarray analysis on RNA from the placentas and livers of neonatal cloned mice derived by nuclear transfer (NT) from both cultured embryonic stem cells and freshly isolated cumulus cells. Direct compa...

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Detalhes bibliográficos
Main Authors: Humpherys, David, Eggan, Kevin, Akutsu, Hidenori, Friedman, Adam, Hochedlinger, Konrad, Yanagimachi, Ryuzo, Lander, Eric S., Golub, Todd R., Jaenisch, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC130555/
https://ncbi.nlm.nih.gov/pubmed/12235366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192433399
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