Infection-specific phosphorylation of glutamyl-prolyl tRNA synthetase induces antiviral immunity

The mammalian cytoplasmic multi-tRNA synthetase complex (MSC) is a depot system that regulates non-translational cellular functions. Here we found that the MSC component glutamyl-prolyl-tRNA synthetase (EPRS) switched its function following viral infection and exhibited potent antiviral activity. In...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Immunol
Autors principals: Lee, Eun-Young, Lee, Hyun-Cheol, Kim, Hyun-Kwan, Jang, Song Yee, Park, Seong-Jun, Kim, Yong-Hoon, Kim, Jong Hwan, Hwang, Jungwon, Kim, Jae-Hoon, Kim, Tae-Hwan, Arif, Abul, Kim, Seon-Young, Choi, Young-Ki, Lee, Cheolju, Lee, Chul-Ho, Jung, Jae U, Fox, Paul L, Kim, Sunghoon, Lee, Jong-Soo, Kim, Myung Hee
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173487/
https://ncbi.nlm.nih.gov/pubmed/27595231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3542
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars