Glutamyl-Prolyl-tRNA Synthetase Regulates Epithelial Expression of Mesenchymal Markers and Extracellular Matrix Proteins: Implications for Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF), a chronic disease of unknown cause, is characterized by abnormal accumulation of extracellular matrix (ECM) in fibrotic foci in the lung. Previous studies have shown that the transforming growth factor β1 (TGFβ1) and signal transducers and activators of transcrip...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Song, Dae-Geun, Kim, Doyeun, Jung, Jae Woo, Nam, Seo Hee, Kim, Ji Eon, Kim, Hye-Jin, Kim, Jong Hyun, Pan, Cheol-Ho, Kim, Sunghoon, Lee, Jung Weon
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6256097/
https://ncbi.nlm.nih.gov/pubmed/30524284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01337
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