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Activation of CK1ε by PP2A/PR61ε is required for the initiation of Wnt signaling
Canonical Wnt signaling induces the stabilization of β-catenin, its translocation to the nucleus and the activation of target promoters. This pathway is initiated by the binding of Wnt ligands to the Frizzled receptor, the association of the LRP5/6 coreceptor and the formation of a complex comprisin...
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| 出版年: | Oncogene |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5173447/ https://ncbi.nlm.nih.gov/pubmed/27321178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.209 |
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