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Activation of CK1ε by PP2A/PR61ε is required for the initiation of Wnt signaling

Canonical Wnt signaling induces the stabilization of β-catenin, its translocation to the nucleus and the activation of target promoters. This pathway is initiated by the binding of Wnt ligands to the Frizzled receptor, the association of the LRP5/6 coreceptor and the formation of a complex comprisin...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncogene
Päätekijät: Vinyoles, M, Del Valle-Pérez, B, Curto, J, Padilla, M, Villarroel, A, Yang, J, de Herreros, AG, Duñach, M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173447/
https://ncbi.nlm.nih.gov/pubmed/27321178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.209
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