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Coordinated Action of CK1 Isoforms in Canonical Wnt Signaling
Activation of the Wnt pathway promotes the progressive phosphorylation of coreceptor LRP5/6 (low-density lipoprotein receptor-related proteins 5 and 6), creating a phosphorylated motif that inhibits glycogen synthase kinase 3β (GSK-3β), which in turn stabilizes β-catenin, increasing the transcriptio...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3133391/ https://ncbi.nlm.nih.gov/pubmed/21606194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01466-10 |
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