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Thymic dendritic cell subsets display distinct efficiencies and mechanisms of intercellular MHC transfer

Thymic dendritic cells (DC) delete self-Ag-specific thymocytes, and drive development of FoxP3-expressing immunoregulatory T cells. Unlike medullary thymic epithelial cells (mTEC), which express and present peripheral self-Ag, DC must acquire self-Ag to mediate thymic negative selection. One such me...

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書目詳細資料
發表在:J Immunol
Main Authors: Kroger, Charles J., Spidale, Nicholas A., Wang, Bo, Tisch, Roland
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173434/
https://ncbi.nlm.nih.gov/pubmed/27895179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601516
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