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Thymic dendritic cell subsets display distinct efficiencies and mechanisms of intercellular MHC transfer
Thymic dendritic cells (DC) delete self-Ag-specific thymocytes, and drive development of FoxP3-expressing immunoregulatory T cells. Unlike medullary thymic epithelial cells (mTEC), which express and present peripheral self-Ag, DC must acquire self-Ag to mediate thymic negative selection. One such me...
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發表在: | J Immunol |
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Main Authors: | , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
2016
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5173434/ https://ncbi.nlm.nih.gov/pubmed/27895179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601516 |
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