Autophagy-mediated catabolism of visual transduction proteins prevents retinal degeneration

Autophagy is a lysosomal degradation pathway critical to preventing the accumulation of cytotoxic proteins. Deletion of the essential autophagy gene Atg5 from the rod photoreceptors of the retina (atg5(Δrod) mouse) results in the accumulation of the phototransduction protein transducin and the degen...

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Bibliografiska uppgifter
I publikationen:Autophagy
Huvudupphovsmän: Yao, Jingyu, Jia, Lin, Feathers, Kecia, Lin, Chengmao, Khan, Naheed W., Klionsky, Daniel J., Ferguson, Thomas A., Zacks, David N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2016
Ämnen:
Basic Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173283/
https://ncbi.nlm.nih.gov/pubmed/27753525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1238553
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