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Autophagy-mediated catabolism of visual transduction proteins prevents retinal degeneration
Autophagy is a lysosomal degradation pathway critical to preventing the accumulation of cytotoxic proteins. Deletion of the essential autophagy gene Atg5 from the rod photoreceptors of the retina (atg5(Δrod) mouse) results in the accumulation of the phototransduction protein transducin and the degen...
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| Publicado no: | Autophagy |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5173283/ https://ncbi.nlm.nih.gov/pubmed/27753525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1238553 |
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