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Protective Effect of Met12, a Small Peptide Inhibitor of Fas, on the Retinal Pigment Epithelium and Photoreceptor After Sodium Iodate Injury

PURPOSE: A major problem in macular degeneration is the inability to reduce RPE and photoreceptor death. These cells die by necroptosis and apoptosis, respectively, but the upstream activator(s) of these death pathways is unknown. In this study, we use the sodium iodate (NaIO3) model of oxidative st...

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Bibliographic Details
Published in:Invest Ophthalmol Vis Sci
Main Authors: Xiao, Jianhui, Yao, Jingyu, Jia, Lin, Lin, Chengmao, Zacks, David N.
Format: Artigo
Language:Inglês
Published: The Association for Research in Vision and Ophthalmology 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374881/
https://ncbi.nlm.nih.gov/pubmed/28346613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-21392
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