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Constitutively active transforming growth factor β receptor 1 in the mouse ovary promotes tumorigenesis
Despite the well-established tumor suppressive role of TGFβ proteins, depletion of key TGFβ signaling components in the mouse ovary does not induce a growth advantage. To define the role of TGFβ signaling in ovarian tumorigenesis, we created a mouse model expressing a constitutively active TGFβ rece...
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| Vydáno v: | Oncotarget |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Impact Journals LLC
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5173031/ https://ncbi.nlm.nih.gov/pubmed/27344183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10149 |
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