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A novel mouse model of testicular granulosa cell tumors

STUDY QUESTION: What is the role of dysregulated transforming growth factor beta (TGFB) signaling in the development of sex cord-stromal tumors in the testis? SUMMARY ANSWER: Overactivation of TGFB signaling results in the development of testicular tumors resembling granulosa cell tumors (GrCTs). WH...

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Bibliographic Details
Published in:Mol Hum Reprod
Main Authors: Fang, Xin, Ni, Nan, Gao, Yang, Vincent, David F, Bartholin, Laurent, Li, Qinglei
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279300/
https://ncbi.nlm.nih.gov/pubmed/29788434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gay023
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