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Dysfunctional Transforming Growth Factor-β Receptor II Accelerates Prostate Tumorigenesis in the TRAMP Mouse Model

The contribution of a dysfunctional TGF-β type II receptor (TGFβRII) to prostate cancer initiation and progression was investigated in an in vivo mouse model. Transgenic mice harboring the dominant-negative mutant TGF-β type II receptor (DNTGFβRII) in mouse epithelial cell were crossed with the TRAM...

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Detalhes bibliográficos
Main Authors: Pu, Hong, Collazo, Joanne, Jones, Elisabeth, Gayheart, Dustin, Sakamoto, Shinichi, Vogt, Adam, Mitchell, Bonnie, Kyprianou, Natasha
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747670/
https://ncbi.nlm.nih.gov/pubmed/19738062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0758
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