Plasma Efavirenz Exposure, Sex, and Age Predict Virological Response in HIV-Infected African Children

BACKGROUND: Owing to insufficient evidence in children, target plasma concentrations of efavirenz are based on studies in adults. Our analysis aimed to evaluate the pediatric therapeutic thresholds and characterize the determinants of virological suppression in African children. METHODS: We analyzed...

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Bibliographic Details
Published in:J Acquir Immune Defic Syndr
Main Authors: Bienczak, Andrzej, Denti, Paolo, Cook, Adrian, Wiesner, Lubbe, Mulenga, Veronica, Kityo, Cissy, Kekitiinwa, Addy, Gibb, Diana M., Burger, David, Walker, A. Sarah, McIlleron, Helen
Format: Artigo
Language:Inglês
Published: JAIDS Journal of Acquired Immune Deficiency Syndromes 2016
Subjects:
Clinical Science
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5172513/
https://ncbi.nlm.nih.gov/pubmed/27116047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001032
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