The impact of genetic polymorphisms on the pharmacokinetics of efavirenz in African children

AIMS: Using a model‐based approach, the efavirenz steady‐state pharmacokinetics in African children is characterized, quantifying demographic and genotypic effects on the drug's disposition. Simulations are also conducted allowing prediction of optimized doses of efavirenz in this population. M...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Bienczak, Andrzej, Cook, Adrian, Wiesner, Lubbe, Olagunju, Adeniyi, Mulenga, Veronica, Kityo, Cissy, Kekitiinwa, Addy, Owen, Andrew, Walker, A. Sarah, Gibb, Diana M., McIlleron, Helen, Burger, David, Denti, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Paediatric Clinical Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917805/
https://ncbi.nlm.nih.gov/pubmed/26991336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12934
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados