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Translational PK/PD of Anti-Infective Therapeutics

Translational PK/PD modeling has emerged as a critical technique for quantitative analysis of the relationship between dose, exposure and response of antibiotics. By combining model components for pharmacokinetics, bacterial growth kinetics and concentration-dependent drug effects, these models are...

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Dettagli Bibliografici
Pubblicato in:Drug Discov Today Technol
Autori principali: Rathi, Chetan, Lee, Richard E., Meibohm, Bernd
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5172400/
https://ncbi.nlm.nih.gov/pubmed/27978987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddtec.2016.08.004
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