Concerns about pharmacokinetic (PK) and pharmacokinetic-pharmacodynamic (PK-PD) studies in the new therapeutic area of COVID-19 infection

In the context of the COVID-19 pandemic, several drugs have been repurposed as potential candidates for the treatment of COVID-19 infection. While preliminary choices were essentially based on in vitro potency, clinical translation into effective therapies may be challenging due to unfavorable in vi...

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Detalhes bibliográficos
Publicado no:Antiviral Res
Main Authors: Venisse, Nicolas, Peytavin, Gilles, Bouchet, Stephane, Gagnieu, Marie-Claude, Garraffo, Rodolphe, Guilhaumou, Romain, Solas, Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2020
Assuntos:
Invited Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351053/
https://ncbi.nlm.nih.gov/pubmed/32659293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2020.104866
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