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Transport of lipophilic carboxylates is mediated by transmembrane helix 2 in multidrug transporter AcrB
The deployment of multidrug efflux pumps is a powerful defence mechanism for Gram-negative bacterial cells when exposed to antimicrobial agents. The major multidrug efflux transport system in Escherichia coli, AcrAB–TolC, is a tripartite system using the proton-motive force as an energy source. The...
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| Publicat a: | Nat Commun |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5171871/ https://ncbi.nlm.nih.gov/pubmed/27982032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13819 |
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