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Transport of lipophilic carboxylates is mediated by transmembrane helix 2 in multidrug transporter AcrB
The deployment of multidrug efflux pumps is a powerful defence mechanism for Gram-negative bacterial cells when exposed to antimicrobial agents. The major multidrug efflux transport system in Escherichia coli, AcrAB–TolC, is a tripartite system using the proton-motive force as an energy source. The...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5171871/ https://ncbi.nlm.nih.gov/pubmed/27982032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13819 |
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