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Allosteric drug transport mechanism of multidrug transporter AcrB
Gram-negative bacteria maintain an intrinsic resistance mechanism against entry of noxious compounds by utilizing highly efficient efflux pumps. The E. coli AcrAB-TolC drug efflux pump contains the inner membrane H(+)/drug antiporter AcrB comprising three functionally interdependent protomers, cycli...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8242077/ https://ncbi.nlm.nih.gov/pubmed/34188038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24151-3 |
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