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Regulation of Human Organic Anion Transporter 4 by Protein Kinase C and NHERF-1: Altering the Endocytosis of the Transporter
PURPOSE: Human organic anion transporter 4 (hOAT4) belongs to a family of organic anion transporters that play critical roles in the body disposition of clinically important drugs. We have previously shown that the activity of hOAT4 was down-regulated by activation of PKC and up-regulated by PDZ pro...
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| Veröffentlicht in: | Pharm Res |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5169165/ https://ncbi.nlm.nih.gov/pubmed/20140636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-009-9983-2 |
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