Synapsis of Recombination Signal Sequences Located in cis and DNA Underwinding in V(D)J Recombination

V(D)J recombination requires binding and synapsis of a complementary (12/23) pair of recombination signal sequences (RSSs) by the RAG1 and RAG2 proteins, aided by a high-mobility group protein, HMG1 or HMG2. Double-strand DNA cleavage within this synaptic, or paired, complex is thought to involve DN...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Ciubotaru, Mihai, Schatz, David G.
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 2004
Matèries:	DNA Dynamics and Chromosome Structure
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC516766/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15367690/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.19.8727-8744.2004
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