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Synapsis of Recombination Signal Sequences Located in cis and DNA Underwinding in V(D)J Recombination
V(D)J recombination requires binding and synapsis of a complementary (12/23) pair of recombination signal sequences (RSSs) by the RAG1 and RAG2 proteins, aided by a high-mobility group protein, HMG1 or HMG2. Double-strand DNA cleavage within this synaptic, or paired, complex is thought to involve DN...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2004
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC516766/ https://ncbi.nlm.nih.gov/pubmed/15367690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.19.8727-8744.2004 |
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