Protein Kinases C and D Mediate Agonist-Dependent Cardiac Hypertrophy through Nuclear Export of Histone Deacetylase 5

A variety of stress signals stimulate cardiac myocytes to undergo hypertrophy. Persistent cardiac hypertrophy is associated with elevated risk for the development of heart failure. Recently, we showed that class II histone deacetylases (HDACs) suppress cardiac hypertrophy and that stress signals neu...

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Detalhes bibliográficos
Main Authors: Vega, Rick B., Harrison, Brooke C., Meadows, Eric, Roberts, Charles R., Papst, Philip J., Olson, Eric N., McKinsey, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC516754/
https://ncbi.nlm.nih.gov/pubmed/15367659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.19.8374-8385.2004
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