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Protein Kinases C and D Mediate Agonist-Dependent Cardiac Hypertrophy through Nuclear Export of Histone Deacetylase 5

A variety of stress signals stimulate cardiac myocytes to undergo hypertrophy. Persistent cardiac hypertrophy is associated with elevated risk for the development of heart failure. Recently, we showed that class II histone deacetylases (HDACs) suppress cardiac hypertrophy and that stress signals neu...

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Bibliografische gegevens
Hoofdauteurs: Vega, Rick B., Harrison, Brooke C., Meadows, Eric, Roberts, Charles R., Papst, Philip J., Olson, Eric N., McKinsey, Timothy A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC516754/
https://ncbi.nlm.nih.gov/pubmed/15367659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.19.8374-8385.2004
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