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Tau prions from Alzheimer’s disease and chronic traumatic encephalopathy patients propagate in cultured cells

Tau prions are thought to aggregate in the central nervous system, resulting in neurodegeneration. Among the tauopathies, Alzheimer’s disease (AD) is the most common, whereas argyrophilic grain disease (AGD), corticobasal degeneration (CBD), chronic traumatic encephalopathy (CTE), Pick’s disease (Pi...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Woerman, Amanda L., Aoyagi, Atsushi, Patel, Smita, Kazmi, Sabeen A., Lobach, Iryna, Grinberg, Lea T., McKee, Ann C., Seeley, William W., Olson, Steven H., Prusiner, Stanley B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167200/
https://ncbi.nlm.nih.gov/pubmed/27911827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616344113
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