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Synthesis of a Simplified Triazole Analogue of Pateamine A

Pateamine A is a naturally occurring metabolite extracted from the marine sponge Mycale hentscheli. It exhibits potent cytotoxicity towards cancer cell lines and has been shown to target protein translation initiation via inhibition of the function of eukaryotic initiation factor 4A proteins. We hav...

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Bibliografski detalji
Izdano u:Org Biomol Chem
Glavni autori: Cumming, A. Hemi, Brown, Sarah L., Tao, Xu, Cuyamendous, Claire, Field, Jessica J., Miller, John H., Harvey, Joanne E., Teesdale-Spittle, Paul H.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5166979/
https://ncbi.nlm.nih.gov/pubmed/27180995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ob00086j
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