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Combining triazole ligation and enzymatic glycosylation on solid phase simplifies the synthesis of very long glycoprotein analogues

The solid-phase chemical assembly of a protein through iterative chemoselective ligation of unprotected peptide segments can be followed with chemical and/or enzymatic transformations of the resulting immobilized protein, the latter steps thus benefitting from the advantages provided by the solid su...

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Détails bibliographiques
Publié dans:Chem Sci
Auteurs principaux: Galibert, Mathieu, Piller, Véronique, Piller, Friedrich, Aucagne, Vincent, Delmas, Agnès F.
Format: Artigo
Langue:Inglês
Publié: Royal Society of Chemistry 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085731/
https://ncbi.nlm.nih.gov/pubmed/30155000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc00773a
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