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Synthesis of a Simplified Triazole Analogue of Pateamine A

Pateamine A is a naturally occurring metabolite extracted from the marine sponge Mycale hentscheli. It exhibits potent cytotoxicity towards cancer cell lines and has been shown to target protein translation initiation via inhibition of the function of eukaryotic initiation factor 4A proteins. We hav...

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Publicat a:Org Biomol Chem
Autors principals: Cumming, A. Hemi, Brown, Sarah L., Tao, Xu, Cuyamendous, Claire, Field, Jessica J., Miller, John H., Harvey, Joanne E., Teesdale-Spittle, Paul H.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5166979/
https://ncbi.nlm.nih.gov/pubmed/27180995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ob00086j
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