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Synthesis of a Simplified Triazole Analogue of Pateamine A
Pateamine A is a naturally occurring metabolite extracted from the marine sponge Mycale hentscheli. It exhibits potent cytotoxicity towards cancer cell lines and has been shown to target protein translation initiation via inhibition of the function of eukaryotic initiation factor 4A proteins. We hav...
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| Publicado no: | Org Biomol Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5166979/ https://ncbi.nlm.nih.gov/pubmed/27180995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ob00086j |
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