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Fine-tuning of ULK1 mRNA and protein levels is required for autophagy oscillation
Autophagy is an intracellular degradation pathway whose levels are tightly controlled to secure cell homeostasis. Unc-51–like kinase 1 (ULK1) is a conserved serine–threonine kinase that plays a central role in the initiation of autophagy. Here, we report that upon autophagy progression, ULK1 protein...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5166502/ https://ncbi.nlm.nih.gov/pubmed/27932573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201605089 |
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