Fine-tuning of ULK1 mRNA and protein levels is required for autophagy oscillation

Autophagy is an intracellular degradation pathway whose levels are tightly controlled to secure cell homeostasis. Unc-51–like kinase 1 (ULK1) is a conserved serine–threonine kinase that plays a central role in the initiation of autophagy. Here, we report that upon autophagy progression, ULK1 protein...

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Bibliografiska uppgifter
I publikationen:J Cell Biol
Huvudupphovsmän: Nazio, Francesca, Carinci, Marianna, Valacca, Cristina, Bielli, Pamela, Strappazzon, Flavie, Antonioli, Manuela, Ciccosanti, Fabiola, Rodolfo, Carlo, Campello, Silvia, Fimia, Gian Maria, Sette, Claudio, Bonaldo, Paolo, Cecconi, Francesco
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2016
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5166502/
https://ncbi.nlm.nih.gov/pubmed/27932573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201605089
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