Fine-tuning of ULK1 mRNA and protein levels is required for autophagy oscillation

Autophagy is an intracellular degradation pathway whose levels are tightly controlled to secure cell homeostasis. Unc-51–like kinase 1 (ULK1) is a conserved serine–threonine kinase that plays a central role in the initiation of autophagy. Here, we report that upon autophagy progression, ULK1 protein...

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Bibliografische gegevens
Gepubliceerd in:J Cell Biol
Hoofdauteurs: Nazio, Francesca, Carinci, Marianna, Valacca, Cristina, Bielli, Pamela, Strappazzon, Flavie, Antonioli, Manuela, Ciccosanti, Fabiola, Rodolfo, Carlo, Campello, Silvia, Fimia, Gian Maria, Sette, Claudio, Bonaldo, Paolo, Cecconi, Francesco
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2016
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5166502/
https://ncbi.nlm.nih.gov/pubmed/27932573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201605089
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