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Novel regulatory mechanisms for the Dbl family guanine nucleotide exchange factor Cool-2/α-Pix
The Cool-2 (cloned-out of library-2) protein (identical to α-Pix for Pak-interactive exchange factor) has been implicated in various biological responses including chemoattractant signaling and in certain forms of mental retardation. We show that when Cool-2 exists as a dimer, it functions as a Rac-...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC516622/ https://ncbi.nlm.nih.gov/pubmed/15306850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600331 |
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