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Phosphorylation of the Cool-1/β-Pix Protein Serves as a Regulatory Signal for the Migration and Invasive Activity of Src-transformed Cells

Previously we showed that Cool-1 (Cloned out of library-1)/β-Pix (Pak-interactive exchange factor) is phosphorylated at a specific tyrosine residue (Tyr-442) in a Src-dependent manner and serves as a dual function guanine nucleotide exchange factor (GEF)/signaling-effector for Cdc42 that is essentia...

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Bibliografiske detaljer
Main Authors: Feng, Qiyu, Baird, Dan, Yoo, Sungsoo, Antonyak, Marc, Cerione, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881803/
https://ncbi.nlm.nih.gov/pubmed/20375009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.098079
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