Cool-associated Tyrosine-phosphorylated Protein 1 Is Required for the Anchorage-independent Growth of Cervical Carcinoma Cells by Binding Paxillin and Promoting AKT Activation

Cool-associated tyrosine-phosphorylated protein 1 (Cat-1) is a signaling scaffold as well as an ADP-ribosylation factor-GTPase-activating protein. Although best known for its role in cell migration, we recently showed that the ability of Cat-1 to bind paxillin, a major constituent of focal complexes...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Yoo, Sungsoo M., Latifkar, Arash, Cerione, Richard A., Antonyak, Marc A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2017
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339775/
https://ncbi.nlm.nih.gov/pubmed/28100775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.769190
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