Myosin II directly binds and inhibits Dbl family guanine nucleotide exchange factors: a possible link to Rho family GTPases

Cell migration requires the coordinated spatiotemporal regulation of actomyosin contraction and cell protrusion/adhesion. Nonmuscle myosin II (MII) controls Rac1 and Cdc42 activation, and cell protrusion and focal complex formation in migrating cells. However, these mechanisms are poorly understood....

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Bibliographic Details
Main Authors: Lee, Chan-Soo, Choi, Chang-Ki, Shin, Eun-Young, Schwartz, Martin Alexander, Kim, Eung-Gook
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2010
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928003/
https://ncbi.nlm.nih.gov/pubmed/20713598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201003057
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