Immune Cell Profiling of IFN-λ Response Shows pDCs Express Highest Level of IFN-λR1 and Are Directly Responsive via the JAK-STAT Pathway

The interferon lambda (IFN-λ) cytokines have well-known antiviral properties, yet their contribution to immune regulation is not well understood. Epithelial cells represent the major target cell of IFN-λ; peripheral blood mononuclear cells are generally considered nonresponsive, with the exception o...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Interferon Cytokine Res
Auteurs principaux: Kelly, Aoife, Robinson, Mark W., Roche, Gerard, Biron, Christine A., O'Farrelly, Cliona, Ryan, Elizabeth J.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2016
Sujets:
Research Reports
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5165669/
https://ncbi.nlm.nih.gov/pubmed/27617757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2015.0169
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires