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Genetic and mechanistic diversity of piRNA 3' end formation

Small regulatory RNAs guide Argonaute (Ago) proteins in a sequence-specific manner to their targets and thereby play important roles in eukaryotic gene silencing1. Of the three small RNA classes, microRNAs and siRNAs are processed from double-stranded precursors into defined 21- to 23-mers by Dicer,...

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發表在:Nature
Main Authors: Hayashi, Rippei, Schnabl, Jakob, Handler, Dominik, Mohn, Fabio, Ameres, Stefan L., Brennecke, Julius
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5164936/
https://ncbi.nlm.nih.gov/pubmed/27851737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20162
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