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piRNA-guided slicing specifies transcripts for Zucchini dependent, phased piRNA biogenesis
In animal gonads PIWI-clade Argonaute proteins repress transposons sequence-specifically via bound piRNAs. These are processed from single-stranded precursor RNAs by largely unknown mechanisms. Here we show that primary piRNA biogenesis is a 3′ directed and phased process that, in the Drosophila ger...
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| Publicado no: | Science |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4988486/ https://ncbi.nlm.nih.gov/pubmed/25977553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa1039 |
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