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The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis

PIWI-family proteins and their associated small RNAs (piRNAs) act in an evolutionarily conserved innate immune mechanism that provides an essential protection for germ cell genomes against the activity of mobile genetic elements(1). piRNA populations comprise a molecular definition of transposons th...

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Bibliografske podrobnosti
Main Authors: Ipsaro, Jonathan J., Haase, Astrid D., Knott, Simon R., Joshua-Tor, Leemor, Hannon, Gregory J.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493678/
https://ncbi.nlm.nih.gov/pubmed/23064227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11502
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