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Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons

The piRNA pathway safeguards genomic integrity by silencing transposable elements (transposons) in the germline. While Piwi is the central piRNA factor, others including Asterix/Gtsf1 have also been demonstrated to be critical for effective silencing. Here, using eCLIP with a custom informatic pipel...

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Bibliografiska uppgifter
I publikationen:Cell Rep
Huvudupphovsmän: Ipsaro, Jonathan J., O’Brien, Paul A., Bhattacharya, Shibani, Palmer, Arthur G., Joshua-Tor, Leemor
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283736/
https://ncbi.nlm.nih.gov/pubmed/33789107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108914
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