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Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons

The piRNA pathway safeguards genomic integrity by silencing transposable elements (transposons) in the germline. While Piwi is the central piRNA factor, others including Asterix/Gtsf1 have also been demonstrated to be critical for effective silencing. Here, using eCLIP with a custom informatic pipel...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Ipsaro, Jonathan J., O’Brien, Paul A., Bhattacharya, Shibani, Palmer, Arthur G., Joshua-Tor, Leemor
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283736/
https://ncbi.nlm.nih.gov/pubmed/33789107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108914
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