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Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons

The piRNA pathway safeguards genomic integrity by silencing transposable elements (transposons) in the germline. While Piwi is the central piRNA factor, others including Asterix/Gtsf1 have also been demonstrated to be critical for effective silencing. Here, using eCLIP with a custom informatic pipel...

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Detalles Bibliográficos
Publicado en:Cell Rep
Main Authors: Ipsaro, Jonathan J., O’Brien, Paul A., Bhattacharya, Shibani, Palmer, Arthur G., Joshua-Tor, Leemor
Formato: Artigo
Idioma:Inglês
Publicado: 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283736/
https://ncbi.nlm.nih.gov/pubmed/33789107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108914
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