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T cell–mediated vascular dysfunction of human allografts results from IFN-γ dysregulation of NO synthase
Allograft vascular dysfunction predisposes to arteriosclerosis and graft loss. We examined how dysfunction develops in transplanted human arteries in response to circulating allogeneic T cells in vivo using immunodeficient murine hosts. Within 7–9 days, transplanted arteries developed endothelial ce...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC516264/ https://ncbi.nlm.nih.gov/pubmed/15372109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421767 |
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